No documentation related to hard outcomes, such as macrovascular or microvascular complications, were needed to gain FDA approval for marketing in the U.S., despite the known 2- to 4-fold greater risk for experiencing CV events in individuals living with diabetes
For comparison, the SURMOUNT-1 trial for tirzepatide showed an average of 20.9% weight loss at the highest dose over 72 weeks
Learn dosing protocols, timelines, and what to expect
Shoffner J, Hyams L, Langley GN, Cossette S, Mylacraine L, Dale J, et al
transforaminal (through the opening where the nerve exits the spine), interlaminar (between the layers of the spine), or caudal (through the base of the spine), to ensure optimal relief