The differential diagnosis includes subungual verruca, pyogenic granuloma, glomus tumor, keratoacanthoma, subungual nevus, and epidermoid inclusion cyst as well as malignant lesions, such as carcinoma of the nail bed and subungual melanoma.
The FDA approval process means these medications have been studied in large clinical trial populations, their manufacturing facilities are inspected by the FDA, and their labeling (including dosing instructions, warnings, and side effects) has been reviewed and approved by federal regulators
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Beyond the scale, tirzepatide also tends to work faster