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These receptors are widespread within the human body and present in virtually every organ, making the effects of the melanocortins widespread and varied

DCFH-DA probe for H 2 O 2 -induced ROS Raw 264.7 cells were treated as described previously

doi: 10.1016/j.coph.2007.10.010 149 JungJLeeSMLeeMJRyuJSSongJHLeeJEet al

Struma lymphomatosa (Hashimotos thyroiditis)

The relative effectiveness of peroxiredoxins versus GPxs in modulating intracellular hydrogen peroxide levels has been debated: peroxiredoxins are abundantly expressed and different peroxiredoxin isoforms are also found in the cytosol and mitochondria