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Sato, Yasunori

459 Similarly, leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2), a protein linked to PD, localizes to MAMs, where it enhances PERK-mediated phosphorylation of PARKIN, MARCHF5, and mitochondrial E3 ubiquitin ligase activator of NF-B (MULAN), thereby facilitating the ubiquitination of MFN2

Further research is necessary to address the limitations of this study and assess outcomes with semaglutide 2.4 mg treatment beyond 24 months in order to better understand the real-world, long-term effectiveness of semaglutide 2.4 mg for weight management

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Obesity research, 2(3), 255262