Its a rule of thumb, not a law of physics there are exceptions but as a first-pass filter for will this absorb from the gut, it holds up well
(2006) A single-center, double-blinded, randomized controlled study to evaluate the relative efficacy of sublingual and oral vitamin B-complex administration in reducing total serum homocysteine levels
Maintaining cellular NAD supports mitochondrial function, stress resilience, and metabolic flexibilitykey mechanisms linking NNMT inhibition to improved energy balance (Kannt & Pfenninger, Frontiers in Physiology )
Population Limitations: As noted previously, the trials did not include elderly individuals, pregnant women, children, or those with certain medical conditions
It should be noted that this population has a higher incidence of stomach carcinoma