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It is FDA-cleared to improve the appearance of cellulite and skin laxity on the upper arms, and may also be used to address concerns on areas such as the abdomen, legs, and buttocks

Since the discovery and functional verification of GLP-1 in the 1980s ( However, the therapeutic utility of native GLP-1 was limited by its rapid enzymatic degradation and short plasma half-life, which prompted the development of longer-acting receptor agonists

While monthly GLP-1 formulations may become commercially available soon in higher-income regions, other geographies especially those with high expected biosimilar penetration may continue relying on weekly-dosed drugs for the foreseeable future

Prieto et al

HCPCS J3380 Biologics (IL-23 inhibitor): Risankizumab (Skyrizi, J7999) newer biologic for moderate-to-severe CD