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These studies only show a link between vitamin B12 deficiencies and weight gain, Matthew Cowling, D.O., a physical medicine and rehabilitation specialist in Madison, Wisconsin who specializes in weight loss, previously told The Edge

Why it is effective: Supports fat loss through enhanced GH-mediated lipolysis Preserves and builds lean muscle during caloric restriction Improves recovery, sleep quality, and mood Ideal for age-related metabolic slowdown and body composition changes Common side effects: Injection site reactions, water retention, joint tightness, headaches, and flushing

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