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IGF-1 plays a central role in tissue repair and cell growth but should be used cautiously due to its proliferative effects. Pollak, Nature Reviews Cancer Stacking HGH and IGF-1 increases potential benefitsbut also compounds side effect risks if not carefully managed

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Ben David A, Papir Y, Hazan O, Redelman M, Diamant E, Barnea A, et al

38 , 1544.e11544.e3 (2020)

It is reported that sestrin2 (Sesn2) is a highly evolved, stress-responsive protein essential for oxidative stress resistance