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JAMA Surg 155(5):e200087 Reynolds K, Barton LJ, Basu A et al (2021) Comparative effectiveness of gastric bypass and vertical sleeve gastrectomy for hypertension remission and relapse: the ENGAGE CVD study

PMID: 8053578 Twersky RS, Goel V, Narayan P, Weedon J (2014) The risk of hypertension after preoperative discontinuation of angiotensin-converting enzyme inhibitors or angiotensin receptor antagonists in ambulatory and same-day admission patients

Subsequently, innate immune cells in the brain (microglia, astrocytes, and oligodendroglia) are activated in response to inflammatory stimuli including the production of cytokines, chemokines, and secondary inflammatory mediators such as prostaglandins (77)

Notably, the US label for semaglutide for obesity advises monitoring for depression or suicidal thoughts

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