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benefit was preserved in the prespecified subgroup receiving sodium-glucose cotransporter-2 inhibitors (SGLT2i) at baseline, which supports combined GLP-1RA + SGLT2i use as a supported option pursuing complementary pathways [4], [33]

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This approach highlights how innovation and sustainability can go hand in hand, ensuring that even as drug formulations evolve, delivery systems keep pace with sustainability goals

Carnitine functions as a carrier for acylgroups into and out of the mitochondria (Longo et al., 2016), and acetylcarnitine shuttling from the mitochondria and peroxisome can provide the acetyl groups for histone acetylation (Izzo et al., 2023