In addition, there are multiple other drugs currently under development, including several oral drugs such as Orforglipron from Eli Lilly and Danuglipron from Pfizer, as well as further dual and triple receptor agonists
If the blockage causes a perforation or tear of the intestine, bowel contents could leak out into other parts of the body, putting the patient at risk of life-threatening infections like peritonitis and sepsis
doi: 10.1126/science.aaw5473
The most common ones are digestive, especially early on as your body adjusts
According to an article published in Diabetes Therapy , Co-infusion of GLP-1 and GIP has a synergistic effect, resulting in significantly increased insulin response and glucagonostatic (glucagon stabilizing) response, compared with administration of either hormone alone. In other words, combining GLP-1 and GIP receptor agonists in a single drug appears to have a greater impact on blood sugar control than GLP-1 used alone
