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Key Takeaways Gynecomastia, affecting 35% of men, is often caused by hormonal imbalances and can persist after substantial weight loss, such as semaglutide (Wegovy), a medication which reduces appetite and body weight, but may not affect the glandular breast tissue characteristic of the condition

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Patients taking beta-blockers may have blunted adrenergic symptoms of hypoglycemia (such as tremor and palpitations), making recognition more difficult