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The current model for oleaginocity implicates triacylglycerides (TAGs) as sinks for carbon that would have otherwise been used for cell growth and division (Figure 3)

Studies have shown that, in the cfDNA of patients with stage III or IV CRC, the copy number of key genes related to CRC (RTK, PI3K, and Wnt) is increased, and the copy number of cfDNA changes (CNVs) is positively correlated with tumour progression