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AMP Kinase (AMPK): AMPK, a key energy-sensing kinase, modulates the activity of glutamine-PRPP amidotransferase to ensure that nucleotide synthesis is in sync with cellular energy status

Lifestyle changes in the developed regions of the world and the absence of effective preventive screening programs and healthcare access in some less-developed regions are expected to further increase cancer-related morbidity and mortality in the future (Sung et al., 2021)

The development of effective pharmacotherapies that entail a reduction of adverse effects has hinged on the understanding of the neuroendocrine pathways involved in the homeostatic control of body weight

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