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Lower-dose versions can be obtained over the counter with pharmacist approval

10.1038/s41598-024-84135-3 48 ZhangY.YangY.ChenW.MiC.XuX.ShenY.et al (2023)

Action thresholds at 4 weeks: Serum copper rise of more than 30 g/dL above baseline: reduce dose frequency or hold therapy and recheck in 2 weeks

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What "documented lifestyle intervention failure" actually means This is the requirement that frustrates patients most