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In line with this observation, the pre-administration of DSePA (2 mg/Kg bodyweight) for five consecutive days significantly improved the 30-day survival of mice against the lethal dose (-rays, 10 Gy) of WBI by preventing lipid peroxidation, DNA damage, and apoptosis in the radiosensitive organs like the spleen and small intestine [88, 89]

Only 4.1% of the 4 mg group stopped treatment because of adverse events, compared with 6.9% at 9 mg, 11.3% at 12 mg and 4.9% with placebo

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Sympathetic nerve terminals release dopamine, which binds to dopamine receptors on cells, thereby inhibiting insulin secretion [58]