In fact, it had been documented more than ten years earlier that when ascorbic acid and glutathione are together in the presence of the hexoxidase [ascorbate oxidase] described by Szent-Gyorgyi the glutathione wholly protects the vitamin from oxidation, whilst it is itself oxidized at a rate which, with the same concentration of enzyme, is exactly the same as the rate with which ascorbic acid is oxidized when alone. (Hopkins and Morgan 1938)
Consistency matters more than timing: regular intake builds nitric oxide availability and maintains vascular flexibility
Confounding Variable A factor that is related to both the treatment and the outcome, which can distort the apparent effect if not accounted for
For example, a child with ASD may require therapy, medication, and additional tutoring
In addition, somatic (tumour-specific) mutations have been identified in hormone-producing tumours that cause hypertension (phaeochromocytomas, aldosterone-producing adenomas, cortisol-producing adenomas, pituitary adenomas, reninomas)