5, 6, 8, 13, 14 This indicates that liraglutide treatment uncouples the increase in soluble leptin receptors that normally occurs during weight loss, thereby preventing the decrease in free leptin and thus preventing the increase in food-seeking behavior during weight loss maintenance
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Most adverse effects are dose-dependent, meaning they tend to be less severe at lower doses
Additionally, the reduced reliance on exogenous insulin further supports the therapys effectiveness in delaying disease progression