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Considerable efforts have been made to investigate the central pathological features of these diseases, giving rise to numerous attempts to develop compounds that interfere with such features

In many cases, adjustments to dosing or additional support can make treatment tolerable

Fasting and Postprandial Glucose In a clinical study in adults with type 2 diabetes mellitus, treatment with once weekly BYDUREON resulted in mean reductions in fasting plasma glucose of -45 mg/dL and 2-hour PPG concentrations of -95 mg/dL

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Autoradiographic localization of receptors for glucagon-like peptide-1 (7-36) amide in rat brain