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Effects of metformin on learning and memory behaviors and brain mitochondrial functions in high fat diet induced insulin resistant rats

As the body keeps getting glucose for several hours, energy is steadily produced, and the person remains active for longer

These findings reinforce the importance of preconception counseling, folic acid supplementation, and addressing modifiable risk factors before pregnancy

Both outcomes are clinically meaningful, but they illustrate why BMI at treatment initiation shapes expectations about results

Indeed, TMPRSS2 also caused a loss of the surface FLAG tag in cells transfected with PAR2-WT, but, remarkably, not with PAR2-G37I (Figure 2B)