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it occurs suddenly and lasts for a short period of time, can lead to systemic inflammation, shock, and death, and needs to be treated aggressively

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Hormonal and blood-sugar disruption, including elevated cortisol and prolactin, reduced insulin sensitivity, and hypoglycemia risk tied to IGF-1 receptor activity

Theoretically, chronic lipolysis activation could deplete essential lipid stores or disrupt adipose tissue-derived signaling pathways (via adipokines), though this remains speculative