Effective interventions exist, and addressing incontinence early prevents the compensatory behaviors, like limiting fluid intake, that can actually increase UTI risk
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Furthermore, it was stated that clinicians must consider treating patients with T2D and NAFLD with PIO, GLP-1R agonists or sodium-glucose co-transporters 2 (SGLT2) inhibitors to reduce their significant cardiovascular risk
Activation upregulates anorexigenic pathways such as proopiomelanocortin (POMC) neurons, which increase satiety signals and reduce meal size and frequency