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Uniprot P36969-2) is constituted by a catalytic tetrad that consists of the following residues: selenocysteine (Sec 46 ), glutamine (Gln 81 ), tryptophan (Trp 136 ) and asparagine (Asn 137 ) [35]

2008 Jul 1;181(1):795-807 19

When acne scores taken after 1, 2, 3, 4, and 6 weeks of use were compared to baseline, there was no change after 1 week of product use. There was a 7.1%, 21.4%, 28.6% decrease (improvement) in the acne grade after 2, 3 and 4 weeks of product use, respectively. The improvements after 3 and 4 weeks of product use were statistically significant when compared to baseline

Gerriets, V