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[DOI] [PMC free article] [PubMed] [Google Scholar] 151.Goodwin P.J., Chen B.E., Gelmon K.A., Whelan T.J., Ennis M., Lemieux J., Ligibel J.A., Hershman D.L., Mayer I.A., Hobday T.J., et al

Furthermore, the immune systems of older patients, particularly those with NDs, may be compromised, making it difficult to elicit an optimal immune response

As shown in the connected scatterplot in Figure 5 (top), the Sucrosomial B12 formulation rapidly raised circulatory vitamin B12 levels above the deficiency threshold, exceeding 300 pg/mL (borderline level) from day 1, and demonstrated a similar pattern of increasing circulatory vitamin B12 levels over time as observed in the KEMU and LRH studies cohorts, reaching a peak value of 592.7 74.3 at day 7, with all measurements throughout the week being significantly higher than baseline ( p 0.012)