Primary Active Component
However, ferroptosis inducers cannot promote ferroptosis in all cancer cell lines, indicating that the genetic and metabolic susceptibility determinants limit the application of ferroptosis inducers in vivo
Blocking GSH synthesis in combination with JMF4073 depletes dTTP/dCTP pools to eradicate T315I-Bcr-Abl leukemia We hypothesize that reducing the GSH level to increase replication stress can render T315I-Bcr-Abl leukemia more susceptible to JMF4073 in vivo
Peak Energy & Mental Clarity: Coenzyme Q10, Nicotinamide, and B-Vitamins fuel mitochondrial function, boosting cognitive performance, stamina, and overall vitality
YW: Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Validation, Writing review & editing