Safety Gastrointestinal symptoms remained the most frequent adverse effects and followed the familiar pattern seen in earlier GLP-1 studies
The combination of this drug lowers the blood sugar level by increasing the amount of insulin that is released by the pancreas and it also lowers the production of glucose in the liver and delays the glucose absorption from the intestines
Semaglutide is a GLP-1 agonist, Tirzepatide is a dual GLP-1 and GIP agonist, and Retatrutide is a triple GLP-1, GIP, and glucagon agonist
More importantly, the artificial sweeteners replacing that sugar, primarily sucralose, are still being studied for long-term metabolic effects at habitual, high-volume consumption
Researchers should also investigate its potential cardiovascular, neuroprotective, and bariatric surgery-like benefits as hypotheses for future research