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This graphical abstract shows that higher gut hormone levels after bariatric surgery are due to altered flow of nutrients that stimulates more distal enteroendocrine cells

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(5) Thus, it is believed that Sermorelin may retain the core ability of GHRH: to potentially prompt the GHRH receptors in the pituitary gland to intermittently release growth hormone

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For this reason, these medications are often prescribed for managing type 2 diabetes or obesity