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While glutathione is present in all cells, its highest concentration is found in the liver, where it plays an absolutely indispensable role in the body's primary detoxification pathways

Nonetheless, after APAP treatment the expression of antioxidant genes with a prominent role in the glutathione metabolism (Gcl-c, G6pdh and Nqo1) raised in WT mice, while only modestly increased in LivPGC-1 littermates (Fig

[DOI] [PubMed] [Google Scholar] 140.Manolescu B.N., Berteanu M., Cintez D

Additionally, one clinical study reported that consumption of chlorogenic acid-enriched coffee not only improved plasma antioxidant capacity and decreased plasma lipid and protein oxidation but also donated to enhancing cardiovascular health in people with hypercholesterolemia [169]

doi:10.1186/s41043-015-0032-y [28] Woodford KB