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doi: 10.3390/cancers15153777 45 JacksonWCHartmanHEGharzaiLAMaurinoCKarnakDMMendiratta-LalaMet al
Bedford's outdoor culture plays a role too
ARID1A directly binds the Foxa2 promoter to regulate its transcription, and reduced ARID1A correlates with decreased FOXA2 in both human and non-human primate endometriosis models ( DNA methylation modifiers, including DNA methyltransferases (DNMT1, DNMT3A, DNMT3B) and ten-eleven translocation (TET) methylcytosine dioxygenases (TET1, TET2, TET3), show altered expression in endometriosis, though findings may vary due to sample heterogeneity (cell types, menstrual cycle phases)
