2 Importantly, amylin does not blunt the counter-regulatory glucagon response to hypoglycemia, so this suppression is selective for the postprandial, not the fasting or emergency, context
John Wiley & Sons Inc, Hoboken, NJ, USA Dai Z, Lyu W, Xie M et al (2017) Effects of -galactooligosaccharides from chickpeas on high-fat-diet-induced metabolic syndrome in mice
Reduced IGF-binding protein affinity leaves more free peptide for IGF-1 receptor activation, yielding roughly 210 potency vs native IGF-1 in preclinical assays but a very short ~2030 minute half-life
I hereby declare that I do not have a personal or family history of MTC or MEN 2
Lenzi A, Lombardo F, Gandini L, Culasso F, Dondero F