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The authors confirmed that AngIV analogs can inhibit HGF binding to c-Met and HGF-dependent signaling by interfering with HGF dimerization, a crucial step for c-Met activation

de F., Fechine, C

That one time you need it, you'll be glad you have it

In the present work, we used metabolic profiling to determine potential biomarkers of tamoxifen resistance, and gene expression levels of enzymes important to these metabolites and then correlated the expression to the survival of patients receiving tamoxifen