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Moreover, signs of microglia activation as well as increased inflammatory cytokines and chemokines (i.e., interferon (IFN), interleukin (IL)-1, IL-6, tumor necrosis factor (TNF), and chemokine C-C motif ligand (CCL)-2) have been found in the brains and cerebrospinal fluid of ASD subjects [20,41]

Not a vague "brightening promise" a documented result with real participants

This indicates that NNMT could be a potential biomarker for cancer prognosis, and the inhibition of this enzyme through 5 Amino 1 MQ can act as an anti-cancer treatment

Specifically, the upregulation of the pro-inflammatory cytokine TNF- in the brain activates its receptors (TNFR1 & TNFR2)

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