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Vitamin B12 primarily comes from animal-based products, which makes those who follow vegetarian and vegan diets more likely to develop vitamin deficiency

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Data availability The protein structure from accession codes 1e17 (FOXO4 FHD) was obtained from the PDB at All other data are available from the corresponding author upon reasonable request

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In our official GST affinity purification protocol we recommend using 1x PBS, pH 7.3 as the binding buffer