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Hypertrophic adipocytes can promote the infiltration of macrophages into adipose tissue, thereby creating a local microenvironment characterized by a pro-inflammatory state, manifested by increased production of various cytokines, including tumor necrosis factor- (TNF-), interleukin-6 (IL-6), and chemokines
Oxidative stress and inflammation have been found to increase the severity of COVID-19 symptoms, especially in people with comorbidities
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Neurology (2005) 64:108890.10.1212/01.WNL.0000154641.08211.B7 90 RamaekersVTRothenbergSPSequeiraJMOpladenTBlauNQuadrosEVet alAutoantibodies to folate receptors in the cerebral folate deficiency syndrome