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A randomized, double-blind phase I/IIa study of intranasal glutathione in Parkinson's disease

After the introduction of NGS technology, many variants have been described for each PFIC-related gene, and new ones are frequently identified

In the brain, dopamine functions as a neurotransmittera chemical released by neurons (nerve cells) to send signals to other nerve cells

This is one of the most critical points that many people overlook

Importantly, functional B12 deficiency can sometimes coexist with high total B12 levels, especially in kidney disease, and may require additional testing with methylmalonic acid (MMA) or holotranscobalamin if deficiency is suspected clinically