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The study confirmed that impairment of the GSH redox cycle but not inhibition of catalase dramatically increased susceptibility of pulmonary artery endothelial cells to H2O2-mediated attack

Additionally, in young overweight patients with IR and PCOS, a 12-month regimen of metformin therapy demonstrated a significant reduction in the prevalence of MS and amelioration of liver complications, enhancing insulin sensitivity ( Therefore, metformin has demonstrated efficacy in the management of PCOS in conjunction with MASLD, particularly in overweight and obese females with PCOS and IR

doi: 10.1016/j.plaphy.2014.06.008

JH: Data curation, Investigation, Methodology, Validation, Writing review and editing