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Possibly, in the absence of GPx-1, accumulated oxidants may oxidatively damage proteins involved in signaling to suppress survival responses

Procedia of Multidisciplinary Research , 4 (5)

Flores-Guerrero, University College London, United Kingdom Christos Stefanis, Democritus University of Thrace, Greece Updates Copyright 2025 Wang, Ni, Zhou, Peng, Cao, Zhu, Gong, Lu, Han, Lin and Wang

Although few clinical trials have focused on the efficacy of SFN in the treatment of liver diseases, previous findings from preclinical studies are exciting, especially in fatty liver disease

Deficits in B vitamins can raise homocysteine levels, which can then cause DNA damage, oxidative stress, and a persistent inflammatory state that can modify epigenetics and cause cancer (170)