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Our study illustrates the importance of studying ciliopathies, not only as rare genetic disorders but also as critical contributors to metabolic dysregulation in more prevalent forms of obesity

Deane AM, Chapman MJ, Horowitz M

Epigenetic dysregulation in IR Recent studies have suggested that epigenetic modifications such as DNA methylation (DNAm) and histone post-translational modifications (PTM) are implicated in the development of systemic IR

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Monitoring priorities for a person on both would therefore differ from monitoring for either alone another reason this is a supervised decision rather than a self-directed one