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However, Zhao et al

An acidic or basic constituent also contributes to specific interactions in solutions from the Lewis electron donor-acceptor point of view

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While glia-derived glutamine provides 50-60% of glutamate neurotransmitter, when the pathway is blocked with MeAIB excitatory transmission abruptly decreases but rapidly recovers, consistent with endogenous neuronal sources of glutamate neurotransmitter (15)