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Conversely, SIRT3 overexpression has the opposite effects, 105 suggesting that SIRT3 inhibits AKT-dependent mitochondrial metabolism and EMT, thereby promoting ferroptosis
GLP-1 agonists are a class of medications that mimic the effects of glucagon-like peptide-1 (GLP-1) a naturally occurring hormone in the body
10.1016/j.euroneuro.2017.11.010
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In the 20-week study, participants receiving exenatide once-monthly achieved similar improvements in blood glucose control (average A1c reductions between 1.3% and 1.5%) as those receiving Bydureon (average A1c reduction of 1.5%)
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