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Doses exceeding ~200300 mg/day should generally be reserved for supervised therapeutic use due to potential for metabolic byproduct accumulation [15]

Among other things, he noted, this could help establish a recommended dose

Effects of alternate day fasting and exercise on cholesterol metabolism in overweight or obese adults: A pilot randomized controlled trial

O., Fedorovich, M

Systematic reviews and meta-analyses in the endocrinology literature indicate that visceral fat reduction decreases peripheral aromatisation of testosterone to oestrogen, which can improve the hormonal profile