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Patients with a history of diabetic retinopathy should be monitored for progression of diabetic retinopathy Hypoglycemia: Patients receiving RYBELSUS in combination with an insulin secretagogue (e.g., sulfonylurea) or insulin may have an increased risk of hypoglycemia, including severe hypoglycemia

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This includes individuals with prediabetes (HbA1c 5.76.4%, fasting glucose 100125 mg/dL, or 2-hour glucose 140199 mg/dL on oral glucose tolerance testing) who have elevated BMI and have not achieved adequate results with lifestyle interventions

Your expert will be able to provide guidance and make any necessary modifications in line with your developments