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Part of the issue is that the approved form of semaglutide can be acquired only from Novo Nordisk, the patent holder for Ozempic and Wegovy, and the company doesn't share drug ingredients with compounding pharmacists, Susan McCoy , executive director of the Mississippi Board of Pharmacy, told NBC News

Real-world data collected outside of clinical trials shows a similar pattern, with tirzepatide patients typically losing several more kilograms on average than semaglutide patients over the same treatment window, though both groups still see meaningful, clinically significant results

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