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If you didn't laugh you'd drive yourself mad

The medicine has progressed through Phase 2 clinical trials , where participants achieved: Dose-dependent weight loss of up to 24.2% after 48 weeks at higher doses 83% of participants at the maximum 12 mg dose losing 15% or more of their body weight All patients taking 8 mg or above are achieving at least 5% weight loss Larger Phase 3 trials are now underway to confirm these findings in broader, more diverse patient groups and to build longer-term safety data

Expert Opin Ther Targets 20(2):179191

In pregnant women in The Gambia, for example, EGR AC values fell in association with a decline in body weight during the rainy season, despite evidence that malnutrition had actually increased (Bates et al., 1981)

Nevill CR, Cooper NJ, Sutton AJ