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As a peptide, Epitalon faces major pharmacokinetic challenges, particularly poor oral bioavailability due to enzymatic degradation in the gut

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While body weight increased over time in both the Donor+Cas9-treated and normal diet-fed mice, the Saline group exhibited a more rapid weight gain, resulting in a gradual decline in the relative body weight of the Donor+Cas9 and normal diet-fed groups (Fig