Chronic mitochondrial ROS generation contributes to DNA damage, protein carbonylation, lipid peroxidation, and the inflammation patterns that accelerate aging across all tissue types
However, as with any medical treatment, its important to be aware of possible interactions with other medications you may be taking
Interestingly, in one article, where the antioxidant properties of Epitalon were investigated, the authors presented a different chemical structure of Epitalon, composed of the same amino acids but bonded in a different way [ 12 ]
Studies into the molecular mechanisms underlying the time of day differences post ischemia revealed that ischemic/reperfusion injury at ZT 18 had reduced infarct volume, edema, neurological deficits, apoptotic death, and improved neuronal survival compared to other time points (ZT0, ZT6, ZT12, and ZT18), coinciding with a decrease in PRAS40 and increased expression of Bmal1, Per1, Clock, AKT, Erk-1/2, mTOR, S6 , and BAD (Beker et al., 2018)
He acknowledged that many of these products havent undergone thorough human testing
