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In this review I aim to re-examine the contested concept of food addiction as a disease in the context of emerging GLP-1based obesity pharmacotherapies, integrating perspectives from neurobiology, societal impacts, and early evidence for their potential application in other substance-use disorders
The bioactivity and action of endogenous incretin hormones are limited through proteolytic cleavage and inactivation by the serine protease dipeptidyl peptidase-4 (DPP4) and renal elimination (10, 11)
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JAMA 2021;325(14):140313
Ding Y, Wang Z, Wang Y, Geng Y, Wen X, Li Y
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