Notably, the age-dependent decline in the exendin-4 induced -cell proliferation was not related to changes of GLP-1R expression, as also indicated by preservation of exendin-4-induced insulin secretion in the adult islets [557]
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In Day 12 DMF-treated SCD erythroblasts, we observed a global increase of 5hmC levels, though no obvious effect on 5mC was detected (Fig