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Rutaecarpine may improve neuronal injury, inhibits apoptosis, inflammation and oxidative stress by regulating the expression of ERK1/2 and Nrf2/HO-1 pathway in rats with cerebral ischemia-reperfusion injury

chinensis is generally well tolerated at moderate doses, with short-term use associated with few reported adverse effects

Environmental factors affecting indole production in Escherichia coli

-LA, a naturally occurring dithiol with antioxidant and anti-inflammatory function, can decrease the interaction between Nrf2 and Keap1, inhibit the pro-inflammatory cytokine IL-8 production and minimize the infection via the Nrf2/HO-1 pathway in the AGS cells (161)