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Renal AOE status There was no significant difference in total SOD activity (Figure 1), and mRNA levels of CuZn-SOD or Mn-SOD (Table 2) between SHR and age-matched WKY

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Mechanistic investigations associate these outcomes with signaling pathways involving vascular endothelial growth factor receptor-2 (VEGFR-2) and downstream Akt-eNOS activation, processes that collectively facilitate efficient muscle tissue remodeling (5)

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